What is tramadol?
Tramadol is a (synthetic opioid) drug used to treat moderately severe pain. This drug is similar to narcotic analgesics. It is used to treat chronic pain where other pain killers are no longer effective. Tramadol is prescribed upon prescription only.
How Tramadol Works?
Tramadol works on neurons in the brain and produce its therapeutic effects. It mainly works on the µ receptors to produce the effects in a dose dependant manner.
How Long Does It Take to Feel the Effects?
Tramadol is available in immediate release and extended release formulations. When taken orally immediate release formulation produce effects within one hour. Tramadol is also available in injection.
How long does Tramadol stay in your System
Blood: Tramadol can be detected in blood for up to 2 days after it’s taken
Saliva: Tramadol can be detected in saliva for up to 2 days after it’s taken
Urine: Tramadol can be detected in urine for 3-4 days after it’s taken
Hair: Tramadol can be detected in hair for 30 – 90 days after it’s taken
Factors that affect how long tramadol stays in your body?
A number of factors can affect how long it stays in your body. These include:
Dosage: If you take an overdose of tramadol than prescribed, the longer tramadol will stay in your system.
Route of administration: If tramadol taken in the form of drops and injections excreted faster than other forms of medication like tablets and capsules.
Frequency of use: If you take tramadol frequently, it stays in your system for a longer period of time. A single dose will take short time to get rid of.
Sex and Age: Tramadol may stay in women longer than in men because of higher tramadol concentration in women than in men. Tramadol may stay in an older people than in a younger people.
Metabolism: If your metabolism is slow, it may take your body longer to get rid of tramadol. The metabolic rate is affected by your physical activity, age, diet and genetics.
Reduced function of the organs: If your kidney or liver are not functioning properly, it will stay longer in your body.
Side Effects of Tramadol
If you take an overdose of tramadol than prescribed, side effects also increases. The severity of the side effects depends on the dosage of tramadol you have taken. There is a range of side effects due to overdose of tramadol and following are the some of the common side effects.
- Weakness
- Sweating
- Nausea or vomiting
- Headache
- Sedation or fatigue
- Dizziness
- Dry mouth
- Itching
- Depressed mood
- Irritability
- Constipation
- Slower rate of breathing
- Muscle weakness
- Seizures
- Slow pulse
- Unconsciousness
Treatment for Tramadol Addiction
Chronic usage of tramadol causes addiction both physical and mental dependence. Physical Withdrawal and detoxification symptoms include flu like. Psychological effects may lasts longer. Dose tapping and administration of low dose of benzodiazepines are used to relieve psychological effects it may take a month or two.
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Prof. Venkata Kiran Kumar Mandlem is Head Of Department in CMR College of pharmacy Hyderabad . He Completed PhD in Pharmaceutical Sciences from Andhra University . More info about him MV Kiran Linkedin