What is Lisinopril and why it’s used?

Lisinopril is a prescription medicine and is available as an oral tablet and an oral solution. Lisinopril is used to treat high blood pressure by relaxing the blood vessels in your body and is known as angiotensin-converting enzyme inhibitor, means that inhibits the functioning of a substance in the body that causes blood vessels to constrict. Lisinopril is also used to treat heart failure.

How to take the medicine

You can take lisinopril once a day with or without food. Consult your doctor to decide your dose of medicine. The starting dose is in between 2.5mg and 10mg once a day and the dose of medicine depend on the purpose of you administer.

High blood pressure: 20mg once a day

Diabetic kidney disease: 10mg to 20mg once a day

After a recent heart attack: 10mg once a day

Heart failure: 20mg to 20mg once a day

The dosage will be increased gradually over a few weeks.

How Long Does Lisinopril Stay in Your System?

In most of the people the half-life of lisinopril is about 12 but People with kidney problems will retain more of the drug for a longer period of time and the complete elimination of a substance takes between four and six half-lives in most people. The half-life represents the time it takes a normal person’s metabolism to reduce the concentration of a particular substance by half. Thus, the drug would fully be eliminated from the system within three to four days in most people. Several factors affect how long lisinopril would stay in your body and how long it would be detectable on various drug tests.

The following are the main factors determine how long drugs stay in your system:

Genetics
Age
Sex
Weight and metabolism
How long a person has been taking lisinopril
Amount of drug(s) used
Medical conditions that impact drug elimination
The type of test including urine, blood, or saliva testing

If the liver and kidney functions are healthy, the body will break the drug down at a faster rate.

Lisinopril detection times by drug testing method:

Blood: Lisinopril can be detected in blood for up to 3 days after it’s taken

Saliva: Lisinopril can be detected in saliva for up to 24 hours -3 days after it’s taken

Urine: Lisinopril can be detected in urine up to 2-4 days after it’s taken

Hair: Lisinopril can be detected in hair for up to 30 – 90 days after it’s taken

Lisinopril can cause a number of side effects and are as follows:

Common Side effects

The common side effects with lisinopril include:

Headache
Dizziness
Cough
Diarrhea
Chest pain
Skin rash
Low blood pressure
Blurred vision

Serious side effects

The serious side effects with lisinopril include:

Feeling tired, dizzy, sore throat, fever
Severe stomach pain
Lung problems including shortness of breath and tightening of the chest
Allergic reaction include swelling of your face, lips, tongue or throat
Kidney problems including swelling of your hands, feet, or ankles
Liver problems including yellowing of your skin and the whites of your eyes

Venkata Kiran Kumar Mandlem

Prof. Venkata Kiran Kumar Mandlem is Head Of Department in CMR College of pharmacy Hyderabad . He Completed PhD in Pharmaceutical Sciences from Andhra University . More info about him MV Kiran Linkedin

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