What is Lisinopril and why it’s used?
Lisinopril is a prescription medicine and is available as an oral tablet and an oral solution. Lisinopril is used to treat high blood pressure by relaxing the blood vessels in your body and is known as angiotensin-converting enzyme inhibitor, means that inhibits the functioning of a substance in the body that causes blood vessels to constrict. Lisinopril is also used to treat heart failure.
How to take the medicine
You can take lisinopril once a day with or without food. Consult your doctor to decide your dose of medicine. The starting dose is in between 2.5mg and 10mg once a day and the dose of medicine depend on the purpose of you administer.
High blood pressure: 20mg once a day
Diabetic kidney disease: 10mg to 20mg once a day
After a recent heart attack: 10mg once a day
Heart failure: 20mg to 20mg once a day
The dosage will be increased gradually over a few weeks.
How Long Does Lisinopril Stay in Your System?
In most of the people the half-life of lisinopril is about 12 but People with kidney problems will retain more of the drug for a longer period of time and the complete elimination of a substance takes between four and six half-lives in most people. The half-life represents the time it takes a normal person’s metabolism to reduce the concentration of a particular substance by half. Thus, the drug would fully be eliminated from the system within three to four days in most people. Several factors affect how long lisinopril would stay in your body and how long it would be detectable on various drug tests.
The following are the main factors determine how long drugs stay in your system:
- Weight and metabolism
- How long a person has been taking lisinopril
- Amount of drug(s) used
- Medical conditions that impact drug elimination
- The type of test including urine, blood, or saliva testing
If the liver and kidney functions are healthy, the body will break the drug down at a faster rate.
Lisinopril detection times by drug testing method:
Blood: Lisinopril can be detected in blood for up to 3 days after it’s taken
Saliva: Lisinopril can be detected in saliva for up to 24 hours -3 days after it’s taken
Urine: Lisinopril can be detected in urine up to 2-4 days after it’s taken
Hair: Lisinopril can be detected in hair for up to 30 – 90 days after it’s taken
Lisinopril can cause a number of side effects and are as follows:
Common Side effects
The common side effects with lisinopril include:
- Chest pain
- Skin rash
- Low blood pressure
- Blurred vision
Serious side effects
The serious side effects with lisinopril include:
- Feeling tired, dizzy, sore throat, fever
- Severe stomach pain
- Lung problems including shortness of breath and tightening of the chest
- Allergic reaction include swelling of your face, lips, tongue or throat
- Kidney problems including swelling of your hands, feet, or ankles
- Liver problems including yellowing of your skin and the whites of your eyes
Prof. Venkata Kiran Kumar Mandlem is Head Of Department in CMR College of pharmacy Hyderabad . He Completed PhD in Pharmaceutical Sciences from Andhra University . More info about him MV Kiran Linkedin